eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| rapidly progressive glomerulonephritis | ||||
| Disease ID | 1556 |
|---|---|
| Disease | rapidly progressive glomerulonephritis |
| Definition | Inflammation of the glomeruli that is characterized by a rapid loss in renal function with glomerular crescent formation observed on biopsy; it is often seen in patients with concomitant autoimmune disease, like Goodpasture's syndrome or systemic lupus erythematosus. |
| Synonym | glomerulonephritis rapidly progressive glomerulonephritis, rapidly progressive rapidly progressive glomerulonephritis (disorder) rpgn rpgn - rapidly progressive glomerulonephritis |
| Orphanet | |
| DOID | |
| UMLS | C0221239 |
| SNOMED-CT | |
| Comorbidity | UMLS | Disease | Sentences' Count(Total Sentences:18) C0017658 | glomerulonephritis | 3 C0027697 | nephritis | 2 C0024143 | lupus nephritis | 2 C0403529 | pulmonary-renal syndrome | 1 C0034150 | purpura | 1 C0035078 | renal failure | 1 C0035078 | kidney failure | 1 C0021053 | immune disease | 1 C0014118 | endocarditis | 1 C1136085 | monoclonal gammopathy | 1 C0031069 | familial mediterranean fever | 1 C0042384 | vasculitis | 1 C0014121 | bacterial endocarditis | 1 C0027726 | nephrotic syndrome | 1 C0001824 | granulopenia | 1 C0034155 | thrombotic thrombocytopenic purpura | 1 C0033687 | proteinuria | 1 C0014122 | subacute bacterial endocarditis | 1 |
| Curated Gene | (Waiting for update.) |
| Inferring Gene | (Waiting for update.) |
| Text Mined Gene | Entrez_id | Symbol | Score | Resource(Total Genes:27) 2334 | AFF2 | 1.275 | DISEASES 405 | ARNT | 1.157 | DISEASES 716 | C1S | 1.098 | DISEASES 57126 | CD177 | 1.137 | DISEASES 959 | CD40LG | 2.658 | DISEASES 10878 | CFHR3 | 1.781 | DISEASES 1302 | COL11A2 | 1.675 | DISEASES 1285 | COL4A3 | 3.985 | DISEASES 51428 | DDX41 | 1.761 | DISEASES 2213 | FCGR2B | 1.692 | DISEASES 26762 | HAVCR1 | 1.757 | DISEASES 3123 | HLA-DRB1 | 1.579 | DISEASES 3738 | KCNA3 | 2.281 | DISEASES 3920 | LAMP2 | 1.913 | DISEASES 23569 | PADI4 | 1.037 | DISEASES 23556 | PIGN | 3.992 | DISEASES 5901 | RAN | 1.667 | DISEASES 5923 | RASGRF1 | 2.11 | DISEASES 5962 | RDX | 1.11 | DISEASES 80196 | RNF34 | 2.039 | DISEASES 5265 | SERPINA1 | 1.549 | DISEASES 8710 | SERPINB7 | 2.323 | DISEASES 4184 | SMCP | 2.112 | DISEASES 11346 | SYNPO | 1.224 | DISEASES 117145 | THEM4 | 1.683 | DISEASES 7124 | TNF | 1.448 | DISEASES 7155 | TOP2B | 1.211 | DISEASES |
| Locus | (Waiting for update.) |
| Disease ID | 1556 |
|---|---|
| Disease | rapidly progressive glomerulonephritis |
| Integrated Phenotype | (Waiting for update.) |
| Text Mined Phenotype | HPO | Name | Sentences' Count(Total Phenotypes:14) HP:0000123 | Nephritis | 3 HP:0000099 | Glomerular nephritis | 3 HP:0000083 | Renal insufficiency | 2 HP:0002633 | Vasculitis | 1 HP:0001945 | Fever | 1 HP:0000979 | Purpura | 1 HP:0100584 | Endocarditis | 1 HP:0011034 | Amyloid disease | 1 HP:0001917 | Renal amyloidosis | 1 HP:0001919 | Acute renal failure | 1 HP:0002960 | Autoimmune condition | 1 HP:0000100 | Nephrosis | 1 HP:0000093 | Proteinuria | 1 HP:0006689 | Bacterial endocarditis | 1 |
| Disease ID | 1556 |
|---|---|
| Disease | rapidly progressive glomerulonephritis |
| Manually Symptom | UMLS | Name(Total Manually Symptoms:13) C2697424 | gastric cancer C1963154 | renal failure C1532529 | frosted branch angiitis C1373218 | immunosuppression C0748159 | pulmonary involvement C0242645 | blue toe syndrome C0035078 | kidney failure C0027726 | nephrotic syndrome C0023473 | chronic myelogenous leukaemia C0022661 | chronic renal failure C0022660 | acute renal failure C0011849 | diabetes mellitus C0007134 | renal cell carcinoma |
| Text Mined Symptom | UMLS | Name | Sentences' Count(Total Symptoms:3) |
Manually Genotype(Total Text Mining Genotypes:0) |
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| (Waiting for update.) |
Text Mining Genotype(Total Genotypes:0) | |
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| (Waiting for update.) | |
All Snps(Total Genotypes:0) | |
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| (Waiting for update.) | |
GWASdb Annotation(Total Genotypes:0) | |
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| (Waiting for update.) | |
GWASdb Snp Trait(Total Genotypes:0) | |
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| (Waiting for update.) | |
Mapped by lexical matching(Total Items:0) |
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| (Waiting for update.) |
Mapped by homologous gene(Total Items:0) |
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| (Waiting for update.) |
| Disease ID | 1556 |
|---|---|
| Disease | rapidly progressive glomerulonephritis |
| Case | (Waiting for update.) |